A 51-year-old man is referred to your clinic because of peculiar fundus
findings as seen in the photo above. What other systemic findings would
you most likely find in this patient?
Retina and Vitreous
These excellent photos depict widespread white-centered retinal hemorrhages, known classically as Roth spots.
These lesions are thought to result from the rupture of retinal
capillaries with exudation of whole blood which eventually results in fibrin being deposited in the middle of the hemorrhage.
Roth spots are classically associated with subacute bacterial endocarditis
whose other systemic manifestations include: fever, chills, heart
murmur, splenomegaly, "Janeway lesions" (non-painful erythematous palm
lesions), "Osler's nodes" (tender lesions on toes and fingertips), and splinter hemorrhages of the nailbeds.
Roth spots can also be found in a wide range of other conditions, including: